AustralieFrV1, Main, Exploration, bibRecord, 002148

Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.

Identifieur interne : 002148 ( Main/Exploration ); précédent : 002147; suivant : 002149

Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.

Auteurs : Stéphane Zingue [Brésil] ; Julia Cisilotto [Brésil] ; Alain Brice Tueche [Cameroun] ; Anupam Bishayee [États-Unis] ; Francine Azegha Mefegue [Cameroun] ; Louis Pergaud Sandjo [Brésil] ; Chantal Beatrice Magne Nde [Australie] ; Evelyn Winter [Brésil] ; Thomas Michel [France] ; Derek Tantoh Ndinteh [Afrique du Sud] ; Charline Florence Awounfack [Cameroun] ; Kevine Kamga Silihe [Cameroun] ; Tito Tresor Melachio Tanekou [Cameroun] ; Tânia Beatriz Creczynski-Pasa [Brésil] ; Dieudonné Njamen [Afrique du Sud]

Source :

Journal of ethnopharmacology [ 1872-7573 ] ; 2016.

RBID : pubmed:27267829

Descripteurs français

English descriptors

KwdEn :
- 9,10-Dimethyl-1,2-benzanthracene, Africa, Animals, Anticarcinogenic Agents (chemistry), Anticarcinogenic Agents (isolation & purification), Anticarcinogenic Agents (pharmacology), Anticarcinogenic Agents (toxicity), Antineoplastic Agents, Phytogenic (chemistry), Antineoplastic Agents, Phytogenic (isolation & purification), Antineoplastic Agents, Phytogenic (pharmacology), Antineoplastic Agents, Phytogenic (toxicity), Breast Neoplasms (drug therapy), Breast Neoplasms (genetics), Breast Neoplasms (metabolism), Breast Neoplasms (pathology), Capparaceae (chemistry), Chromatography, Liquid, DNA Damage (drug effects), Dose-Response Relationship, Drug, Ethnobotany, Female, Human Umbilical Vein Endothelial Cells (drug effects), Human Umbilical Vein Endothelial Cells (pathology), Humans, Inhibitory Concentration 50, Lethal Dose 50, MCF-7 Cells, Mammary Neoplasms, Experimental (chemically induced), Mammary Neoplasms, Experimental (pathology), Mammary Neoplasms, Experimental (prevention & control), Medicine, African Traditional, Mice, Molecular Structure, NIH 3T3 Cells, Oxidative Stress (drug effects), Phytotherapy, Plant Extracts (chemistry), Plant Extracts (isolation & purification), Plant Extracts (pharmacology), Plant Extracts (toxicity), Plants, Medicinal, Rats, Wistar, Spectrometry, Mass, Electrospray Ionization, Tamoxifen (pharmacology), Time Factors, Tumor Burden (drug effects).
MESH :
- chemical , chemistry : Anticarcinogenic Agents, Antineoplastic Agents, Phytogenic, Plant Extracts.
- chemical , isolation & purification : Anticarcinogenic Agents, Antineoplastic Agents, Phytogenic, Plant Extracts.
- chemical , pharmacology : Anticarcinogenic Agents, Antineoplastic Agents, Phytogenic, Plant Extracts, Tamoxifen.
- chemical , toxicity : Anticarcinogenic Agents, Antineoplastic Agents, Phytogenic, Plant Extracts.
- chemical : 9,10-Dimethyl-1,2-benzanthracene.
- chemically induced : Mammary Neoplasms, Experimental.
- chemistry : Capparaceae.
- drug effects : DNA Damage, Human Umbilical Vein Endothelial Cells, Oxidative Stress, Tumor Burden.
- drug therapy : Breast Neoplasms.
- genetics : Breast Neoplasms.
- metabolism : Breast Neoplasms.
- pathology : Breast Neoplasms, Human Umbilical Vein Endothelial Cells, Mammary Neoplasms, Experimental.
- prevention & control : Mammary Neoplasms, Experimental.
- Africa, Animals, Chromatography, Liquid, Dose-Response Relationship, Drug, Ethnobotany, Female, Humans, Inhibitory Concentration 50, Lethal Dose 50, MCF-7 Cells, Medicine, African Traditional, Mice, Molecular Structure, NIH 3T3 Cells, Phytotherapy, Plants, Medicinal, Rats, Wistar, Spectrometry, Mass, Electrospray Ionization, Time Factors.

Abstract

Crateva adansonii DC is a plant traditionally used in Cameroon to treat constipation, asthma, snakebites, postmenopausal complaints and cancers.

DOI: 10.1016/j.jep.2016.06.004
PubMed: 27267829

Affiliations:

Afrique du Sud, Australie, Brésil, Cameroun, France, États-Unis
Floride, Santa Catarina

Le document en format XML

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<country xml:lang="fr">Brésil</country>
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<author><name sortKey="Njamen, Dieudonne" sort="Njamen, Dieudonne" uniqKey="Njamen D" first="Dieudonné" last="Njamen">Dieudonné Njamen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé 1, Yaounde, Cameroon; Department of Applied Chemistry, Faculty of Sciences, University of Johannesburg, Doornfontein 2028, South Africa. Electronic address: dnjamen@gmail.com.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé 1, Yaounde, Cameroon; Department of Applied Chemistry, Faculty of Sciences, University of Johannesburg, Doornfontein 2028</wicri:regionArea>
<wicri:noRegion>Doornfontein 2028</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of ethnopharmacology</title>
<idno type="eISSN">1872-7573</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>9,10-Dimethyl-1,2-benzanthracene</term>
<term>Africa</term>
<term>Animals</term>
<term>Anticarcinogenic Agents (chemistry)</term>
<term>Anticarcinogenic Agents (isolation & purification)</term>
<term>Anticarcinogenic Agents (pharmacology)</term>
<term>Anticarcinogenic Agents (toxicity)</term>
<term>Antineoplastic Agents, Phytogenic (chemistry)</term>
<term>Antineoplastic Agents, Phytogenic (isolation & purification)</term>
<term>Antineoplastic Agents, Phytogenic (pharmacology)</term>
<term>Antineoplastic Agents, Phytogenic (toxicity)</term>
<term>Breast Neoplasms (drug therapy)</term>
<term>Breast Neoplasms (genetics)</term>
<term>Breast Neoplasms (metabolism)</term>
<term>Breast Neoplasms (pathology)</term>
<term>Capparaceae (chemistry)</term>
<term>Chromatography, Liquid</term>
<term>DNA Damage (drug effects)</term>
<term>Dose-Response Relationship, Drug</term>
<term>Ethnobotany</term>
<term>Female</term>
<term>Human Umbilical Vein Endothelial Cells (drug effects)</term>
<term>Human Umbilical Vein Endothelial Cells (pathology)</term>
<term>Humans</term>
<term>Inhibitory Concentration 50</term>
<term>Lethal Dose 50</term>
<term>MCF-7 Cells</term>
<term>Mammary Neoplasms, Experimental (chemically induced)</term>
<term>Mammary Neoplasms, Experimental (pathology)</term>
<term>Mammary Neoplasms, Experimental (prevention & control)</term>
<term>Medicine, African Traditional</term>
<term>Mice</term>
<term>Molecular Structure</term>
<term>NIH 3T3 Cells</term>
<term>Oxidative Stress (drug effects)</term>
<term>Phytotherapy</term>
<term>Plant Extracts (chemistry)</term>
<term>Plant Extracts (isolation & purification)</term>
<term>Plant Extracts (pharmacology)</term>
<term>Plant Extracts (toxicity)</term>
<term>Plants, Medicinal</term>
<term>Rats, Wistar</term>
<term>Spectrometry, Mass, Electrospray Ionization</term>
<term>Tamoxifen (pharmacology)</term>
<term>Time Factors</term>
<term>Tumor Burden (drug effects)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>7,12-Diméthyl-benzo[a]anthracène</term>
<term>Afrique</term>
<term>Altération de l'ADN ()</term>
<term>Animaux</term>
<term>Anticarcinogènes ()</term>
<term>Anticarcinogènes (isolement et purification)</term>
<term>Anticarcinogènes (pharmacologie)</term>
<term>Anticarcinogènes (toxicité)</term>
<term>Antinéoplasiques d'origine végétale ()</term>
<term>Antinéoplasiques d'origine végétale (isolement et purification)</term>
<term>Antinéoplasiques d'origine végétale (pharmacologie)</term>
<term>Antinéoplasiques d'origine végétale (toxicité)</term>
<term>Capparaceae ()</term>
<term>Cellules MCF-7</term>
<term>Cellules NIH 3T3</term>
<term>Cellules endothéliales de la veine ombilicale humaine ()</term>
<term>Cellules endothéliales de la veine ombilicale humaine (anatomopathologie)</term>
<term>Charge tumorale ()</term>
<term>Chromatographie en phase liquide</term>
<term>Concentration inhibitrice 50</term>
<term>Dose létale 50</term>
<term>Ethnobotanique</term>
<term>Extraits de plantes ()</term>
<term>Extraits de plantes (isolement et purification)</term>
<term>Extraits de plantes (pharmacologie)</term>
<term>Extraits de plantes (toxicité)</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Médecine traditionnelle africaine</term>
<term>Phytothérapie</term>
<term>Plantes médicinales</term>
<term>Rat Wistar</term>
<term>Relation dose-effet des médicaments</term>
<term>Souris</term>
<term>Spectrométrie de masse ESI</term>
<term>Stress oxydatif ()</term>
<term>Structure moléculaire</term>
<term>Tamoxifène (pharmacologie)</term>
<term>Tumeurs du sein (anatomopathologie)</term>
<term>Tumeurs du sein (génétique)</term>
<term>Tumeurs du sein (métabolisme)</term>
<term>Tumeurs du sein (traitement médicamenteux)</term>
<term>Tumeurs expérimentales de la mamelle ()</term>
<term>Tumeurs expérimentales de la mamelle (anatomopathologie)</term>
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<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Anticarcinogenic Agents</term>
<term>Antineoplastic Agents, Phytogenic</term>
<term>Plant Extracts</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Anticarcinogenic Agents</term>
<term>Antineoplastic Agents, Phytogenic</term>
<term>Plant Extracts</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anticarcinogenic Agents</term>
<term>Antineoplastic Agents, Phytogenic</term>
<term>Plant Extracts</term>
<term>Tamoxifen</term>
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<keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Anticarcinogenic Agents</term>
<term>Antineoplastic Agents, Phytogenic</term>
<term>Plant Extracts</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>9,10-Dimethyl-1,2-benzanthracene</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Cellules endothéliales de la veine ombilicale humaine</term>
<term>Tumeurs du sein</term>
<term>Tumeurs expérimentales de la mamelle</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Mammary Neoplasms, Experimental</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Capparaceae</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>DNA Damage</term>
<term>Human Umbilical Vein Endothelial Cells</term>
<term>Oxidative Stress</term>
<term>Tumor Burden</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Anticarcinogènes</term>
<term>Antinéoplasiques d'origine végétale</term>
<term>Extraits de plantes</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term>
<term>Human Umbilical Vein Endothelial Cells</term>
<term>Mammary Neoplasms, Experimental</term>
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<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Anticarcinogènes</term>
<term>Antinéoplasiques d'origine végétale</term>
<term>Extraits de plantes</term>
<term>Tamoxifène</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Mammary Neoplasms, Experimental</term>
</keywords>
<keywords scheme="MESH" qualifier="toxicité" xml:lang="fr"><term>Anticarcinogènes</term>
<term>Antinéoplasiques d'origine végétale</term>
<term>Extraits de plantes</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Africa</term>
<term>Animals</term>
<term>Chromatography, Liquid</term>
<term>Dose-Response Relationship, Drug</term>
<term>Ethnobotany</term>
<term>Female</term>
<term>Humans</term>
<term>Inhibitory Concentration 50</term>
<term>Lethal Dose 50</term>
<term>MCF-7 Cells</term>
<term>Medicine, African Traditional</term>
<term>Mice</term>
<term>Molecular Structure</term>
<term>NIH 3T3 Cells</term>
<term>Phytotherapy</term>
<term>Plants, Medicinal</term>
<term>Rats, Wistar</term>
<term>Spectrometry, Mass, Electrospray Ionization</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>7,12-Diméthyl-benzo[a]anthracène</term>
<term>Afrique</term>
<term>Altération de l'ADN</term>
<term>Animaux</term>
<term>Anticarcinogènes</term>
<term>Antinéoplasiques d'origine végétale</term>
<term>Capparaceae</term>
<term>Cellules MCF-7</term>
<term>Cellules NIH 3T3</term>
<term>Cellules endothéliales de la veine ombilicale humaine</term>
<term>Charge tumorale</term>
<term>Chromatographie en phase liquide</term>
<term>Concentration inhibitrice 50</term>
<term>Dose létale 50</term>
<term>Ethnobotanique</term>
<term>Extraits de plantes</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Médecine traditionnelle africaine</term>
<term>Phytothérapie</term>
<term>Plantes médicinales</term>
<term>Rat Wistar</term>
<term>Relation dose-effet des médicaments</term>
<term>Souris</term>
<term>Spectrométrie de masse ESI</term>
<term>Stress oxydatif</term>
<term>Structure moléculaire</term>
<term>Tumeurs expérimentales de la mamelle</term>
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<front><div type="abstract" xml:lang="en">Crateva adansonii DC is a plant traditionally used in Cameroon to treat constipation, asthma, snakebites, postmenopausal complaints and cancers.</div>
</front>
</TEI>
<affiliations><list><country><li>Afrique du Sud</li>
<li>Australie</li>
<li>Brésil</li>
<li>Cameroun</li>
<li>France</li>
<li>États-Unis</li>
</country>
<region><li>Floride</li>
<li>Santa Catarina</li>
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<name sortKey="Cisilotto, Julia" sort="Cisilotto, Julia" uniqKey="Cisilotto J" first="Julia" last="Cisilotto">Julia Cisilotto</name>
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<name sortKey="Sandjo, Louis Pergaud" sort="Sandjo, Louis Pergaud" uniqKey="Sandjo L" first="Louis Pergaud" last="Sandjo">Louis Pergaud Sandjo</name>
<name sortKey="Winter, Evelyn" sort="Winter, Evelyn" uniqKey="Winter E" first="Evelyn" last="Winter">Evelyn Winter</name>
</country>
<country name="Cameroun"><noRegion><name sortKey="Tueche, Alain Brice" sort="Tueche, Alain Brice" uniqKey="Tueche A" first="Alain Brice" last="Tueche">Alain Brice Tueche</name>
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<name sortKey="Mefegue, Francine Azegha" sort="Mefegue, Francine Azegha" uniqKey="Mefegue F" first="Francine Azegha" last="Mefegue">Francine Azegha Mefegue</name>
<name sortKey="Melachio Tanekou, Tito Tresor" sort="Melachio Tanekou, Tito Tresor" uniqKey="Melachio Tanekou T" first="Tito Tresor" last="Melachio Tanekou">Tito Tresor Melachio Tanekou</name>
<name sortKey="Silihe, Kevine Kamga" sort="Silihe, Kevine Kamga" uniqKey="Silihe K" first="Kevine Kamga" last="Silihe">Kevine Kamga Silihe</name>
</country>
<country name="États-Unis"><region name="Floride"><name sortKey="Bishayee, Anupam" sort="Bishayee, Anupam" uniqKey="Bishayee A" first="Anupam" last="Bishayee">Anupam Bishayee</name>
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</country>
<country name="Australie"><noRegion><name sortKey="Magne Nde, Chantal Beatrice" sort="Magne Nde, Chantal Beatrice" uniqKey="Magne Nde C" first="Chantal Beatrice" last="Magne Nde">Chantal Beatrice Magne Nde</name>
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</country>
<country name="France"><noRegion><name sortKey="Michel, Thomas" sort="Michel, Thomas" uniqKey="Michel T" first="Thomas" last="Michel">Thomas Michel</name>
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Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.

Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.

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